The integration of Artificial Intelligence (AI) with multimodal imaging has significantly advanced lung cancer diagnosis, offering clinicians enhanced tools for accurate detection and classification. This paper examines the transformative potential of AI-driven multimodal lung cancer diagnosis, focusing on the use of diverse imaging modalities such as Computed Tomography (CT), Positron Emission Tomography (PET), and Magnetic Resonance Imaging (MRI). AI algorithms analyze pixel-level imaging data, extracting intricate features that enable precise tumor characterization. By processing vast amounts of data, AI models can identify subtle patterns and anomalies indicative of lung cancer, surpassing human capabilities for earlier detection and improved patient outcomes. Central to this approach is the development of sophisticated machine learning algorithms, including Convolutional Neural Networks (CNNs) and ensemble methods, trained on large datasets to accurately predict and classify lung cancer. Transfer learning and data augmentation strategies further enhance the models’ robustness, enabling them to perform effectively across diverse populations. AI’s integration into clinical workflows offers realtime support to radiologists, improving diagnostic accuracy through automated image interpretation and decision support systems. While AI-driven lung cancer diagnosis holds great promise, challenges such as patient data privacy, algorithm transparency, and regulatory compliance must be addressed for responsible

implementation. Nevertheless, this approach represents a paradigm shift in oncological care, empowering clinicians with advanced tools for early detection and personalized treatment, ultimately revolutionizing lung cancer diagnosis and management.